Ustekinumab (Stelara ™) and Breastfeeding
Ustekinumab is a disease modifying, biological drug used to treat psoriatic arthritis, plaque psoriasis, Crohns disease, and ulcerative colitis. It is given by sub cutaneous injection. It has a molecular weight 149,000, poor oral bioavailability and milk plasma ratio 0.001 – 0.027 Ustekinumab is a recombinant human monoclonal TNF antibody that binds specifically to TNF- […]
Adalimumab (Humira™) and Breastfeeding
Adalimumab is a disease modifying, biological drug used to treat rheumatoid arthritis, psoriatic arthritis, Crohns disease, ulcerative colitis and Hidradenitis suppurativa. It is given by sub cutaneous injection. It has a molecular weight 148,000. Poor oral bioavailability and relative infant dose 0.12% ( well below 10% regarded as compatible). Adalimumab is a recombinant human monoclonal […]
Raised cholesterol and breastfeeding
When I was working as an independent pharmacist prescriber my main role was to look at primary prevention of cardio vascular disease – identifying factors which raised the risk of people to have a heart attack or stroke in the next 10 years. I used an online calculator using various data like BMI, smoking status, […]